![[Large Capacity] Purcell 88 Billion/mL Glutathione Flexible Liposome 55mL](https://purcell.dev.web360.vn/wp-content/uploads/2025/10/6b72768e4a30c6260da44e89c45f245a-300x300.jpg)
88B/mLL-GLUTATHIONE
FLEXIBLE LIPOSOME
Increase the hit rate without damaging the effective ingredients
Specialized liposomal glutathione in improving pigmentation
Glutathione liposome specialized in improving pigmentation
- 2.7nm elastic liposomes with enhanced pigment targeting rate*
- 88 billion particles per mL of glutathione liposomes*
- 68.7% reduction in melanin pigmentation observed both inside and outside the skin
Increase the hit rate without damaging the effective ingredients
Specialized liposomal glutathione in improving pigmentation
Glutathione liposome specialized in improving pigmentation
*Patent Registration No. 10-2618942
*Confirmation of reduction in melanin pigmentation after application of test product to human skin tissue model / IRB, Yonsei University Severance Hospital January 25, 2023 – February 24, 2023 / GMRC Global Medical Research Center & Yonsei University Severance Hospital Department of Dermatology
*Due to the nature of the raw materials, the efficacy may differ from that of the cosmetic product.
Development Background
What is Glutathione, a powerful natural antioxidant ?
Glutathione is a compound composed of three amino acids: glycine, cysteine, and glutamic acid
. Despite its outstanding antioxidant properties, it’s a tricky ingredient that oxidizes before it’s even absorbed into the skin
. After extensive research, Purcell developed a proprietary ingredient that can deliver its benefits safely and effectively to the target .
1 01. Anti-aging: Naturally produced in the liver, has the function of removing active oxygen and preventing aging.
2 02. Skin whitening: This is a great ingredient that has strong antioxidant effects and prevents melanin production in the skin, thereby providing skin whitening effects.
3 03. Enhances skin immunity: Protects immune cells from damage and maintains balance.
* This is a general characteristic of the raw material and is not related to the effectiveness of the cosmetic.
Topical glutathione** with increased skin availability*
Purcell’s proprietary technology stabilizes high concentrations of glutathione to reach the target point without oxidizing or damaging the active ingredients.
*Skin penetration refers to the extent and speed at which the substance acts on the epidermis of the skin and reaches the target area.
*Limited to raw material characteristics
* Patent registration number 10-2618942
*This is a scene with the epidermis layered for better understanding.
*Actual skin area may differ from image.
Upgraded efficacy verification
The uniqueness and originality of Purcell technology was recognized at the world-renowned international academic conference IFSCC* 2023 .
*IFSCC (International Federation of Cosmetic Chemical Societies) was founded in 1956, it is the largest academic conference in the field of cosmetics with the participation of 81 countries worldwide.
Mechanism 01
The outstanding targeting accuracy of patent-proven elastic liposomes
Glutathione contained in elastic liposomes will change size to 2.7 nm and be absorbed through the pores to reach the target at the end of the skin.
* Patent registration number 10-2618942
*Limited to raw material characteristics
The outstanding targeting accuracy of patent-proven elastic liposomes
| Phân công | Glutathione bình thường | Glutathione được nạp vào liposome nói chung | Glutathione chứa liposome đàn hồi |
|---|---|---|---|
| characteristic | Easily oxidized and cannot be absorbed by the body | Can be absorbed through pores but cannot be absorbed through cells. | Moves to melanin pigment without reducing efficacy |
| Kích thước phân tử | 1.000nm | 186nm | 92-2,7nm |
| Rate of change | 69,3% | 97,2% | |
| Skin permeability | 0% | 30% | 85% |
| cohesion | 0% | 65% | 89% |
89% improvement in skin density after 18 hours of use
| Title | The previous image applies. | The following figure applies | |
|---|---|---|---|
| Elastic liposomes |  |
 |
Skin adhesion +24% compared to conventional liposomes |
| conventional liposomes | |
|
|
|
*This is an internal experiment conducted with raw cosmetic materials for better understanding, not referring to the effectiveness of the cosmetics themselves but only referring to the characteristics of the raw materials. |
|||
Mechanism 02
Synergistic raw material blending and glutathione stabilization technology
It delivers stronger and deeper effects
by blending synergistic ingredients that can stabilize glutathione, a powerful antioxidant, at high concentrations .
Synergistic raw material blending and glutathione stabilization technology
3-step synergistic ingredients: glutathione X tranexamic acid X niacinamide
These three ingredients work together in different ways to improve your skin and restore a more even skin tone.
* References: Desai S, Ayres E, Bak H, Manco M, Lynch S, Raab S, Du A, Green D, Skobowiat C, Wangari-Talbot J, Zheng Q. Effect of Tranexamic Acid, Kojic Acid, and Niacinamide-Containing Serum on Facial Pigmentation Disorders: A Clinical Review. Dermatol Pharmaceutical Journal.1 May 2019;18(5):454-459. PMID: 31141852.
* Limited to raw material characteristics
| Melanin production stage | Efficient raw materials | Effects |
|---|---|---|
| Step 1. Melanin expression |  |
Inhibits tyrosine oxidation and prevents melanin production |
| Step 2. Activate melanin |  |
Inhibits the enzyme that produces melanin pigment |
| Step 3. Move melanin |  |
Inhibits the migration of melanin pigment to the stratum corneum |
Efficacy Verification 01
Superior stability and higher antioxidant effect than the whitening functional ingredient Al-Otin
Commonly known whitening functional ingredients are irritating and sensitive to light, limiting their use. 88B/mL L-Glutathione Flexible Liposome encapsulates glutathione, a powerful antioxidant, in an elastic liposome, providing skin care without the restrictions of light and temperature, and without irritation.
[DPPH Antioxidant Comparison Test]
*The higher the value in the table, the more active oxygen is removed.
[Tyrosinase activity inhibition assay*]
*Lower values indicate inhibition of tyrosine synthesis, promoting melanin production.
Effective verification 02
A 68.7% reduction in melanin pigmentation was confirmed in human skin tissue
After application of Flexible Liposome L-Glutathione 88B/mL, melanin pigmentation was reduced by more than 68% compared to UVB-irradiated skin tissue.
* Confirmation of melanin pigmentation reduction after using the test product on human skin tissue model / IRB, Severance Hospital, Yonsei University January 25, 2023 – February 24, 2023 / GMRC Global Medical Research Center & Department of Dermatology, Severance Hospital, Yonsei University
Experimental results 01
Excellent improvement effect on freckles, even those that have appeared for a long time
After using Flexible Liposome L-Glutathione 88B/mL, melanin
pigmentation was reduced by more than 68% compared to UVB-irradiated skin tissue.
[Measurement of freckle pigmentation: 8.6% reduction in the number of freckles]
Experimental results 02
Confirmed 19.8% reduction in freckle area
Improves pigmentation signs such as freckles and dark spots caused by UV rays and internal and external stimuli.
Experimental results 02
Conclusion
Excellent pigmentation improvement effect confirmed through whitening/antioxidant effects
| Skin lesions | After use |
|---|---|
|
Sign 
|
8.6% improvement in freckles after 4 weeks of use |
|
Blemishes
|
19.8% improvement in pigmentation after 4 weeks |
|
Ton
|
Instant tone improvement 5.5% |
Study Content: GMRC Global Health Research Centre / January 26, 2023 – February 24, 2023 / 20 participants
Improvement in freckles/pigmentation condition after using the product.
Improvement in freckles/pigmentation condition after using the product.
Improvements skin tone (yellow, dark) after using the product.
Improvement in transparency after using the product.
* After applying the test product on humans, the area of freckles/pigmentation, the number of freckles/pigmentation, and skin tone (yellow/dark tone) were measured. Improvement effects were confirmed for old freckles, newly appeared freckles, and skin brightness. 23.01.26~23.02.24 (4 weeks). / GMRC Global Medical Research Center. * Survey response rate (%): Number of subjects who selected 4, 5, or 6 points on a scale of 1 to 6. / Total number of subjects x 100.
-
100%
The number of freckles/pigmentation has improved.
-
100%
Initial signs have improved.
-
100%
Skin tone improved.
Discover our 5% high-content glutathione ampoule, which has been directly confirmed to reduce melanin pigmentation in human skin tissue .
